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Structural analysis and anticomplement activity of a novel homogenous polysaccharide isolated from Juniperus tibetica kom. Li et al. Published online: 7 Aug.
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Volume 38 , Issue 4 December Pages Related Information. Close Figure Viewer. Browse All Figures Return to Figure.

Advances in carbohydrate chemistry and biochemistry

Previous Figure Next Figure. Crawford, of a chapter on the synthesis of r-ascorbic acid provide a comprehensive and authoritative review of the enormous research effort devoted to the synthesis of this important vitamin. The chapter includes extensive details on the synthesis, not only of the vitamin, but also of its precursors. The results of various processes are critically and concisely evaluated. Chemists concerned with the many intermediates and transformations involved in the various syntheses of L-ascorbic acid will find this chapter of great value.

In the first of two chapters devoted to glycoproteins, Montreuil traces the discovery of the important concept that glycan moieties actually serve ;ls biological information-carriers. Development of vastly improved physical, chemical, and enzymic methodologies has led to the determination of definitive structures for many glycoprotein glycans. The chapter is concluded with a discussion of the many possible applications of neoglycoproteins. The final chapter, by Jeffrey and Sundaralingam, is a bibliography of crystal structures that were published in for carbohydrates, nucleosides, and nucleotides.

As in Volumes 32 and 34, the clear, graphic depictions of structure were computer-generated from the original coordinates.

A polysaccharide immunomodulator with therapeutic implications, carbohydrate vaccines, new findings emphasizing the influence of carbohydrate decoration on the regulation of inflammatory response and new therapeutic approaches in the treatment of acute and chronic inflammatory diseases, recent approachesin the treatment of acute and chronic inflammatory diseases, recent progress on glycoengineering based on a glycosylation, and key aspects of the glycosylation changes associated with bladder cancer are amongst the subjects presented in this volume.

The contribution of glycochemistry to innovation in glycosciences is shown with chapters covering highly functionalized exo-glycals for the generation of molecular diversity in a chemoselective manner, imino sugar glycosidase inhibitors, carbasugars, multivalent glycoconjugates, including glycodendrimers, glyconanotubes, and glyconanoparticles, and their uses in medicinal chemistry, as well as artificial saccharide-based and saccharide functionalized gene delivery systems.

Siderphores based on monosaccharides which have proven effective for Gram-negative bacteria and mycobacteria , and the so-called smart materials, which can modulate and control cell behaviour , complete the volume.


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Volume 38 of Carbohydrate Chemistry - Chemical and Biological Apporaches contains contributions ranging from glycochemistry to glycobiology. This collection demonstrates in a meaningful way how the interdisciplinary approach of an international glyconetwork can advance the field of carbohydrate research in Europe and worldwide. Jump to main content.

Carbohydrate Chemistry (RSC Publishing)

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